Clinical research of cerebral oxygen saturation goal-oriented anesthesia management in optimizing the wake-up test during spinal orthopedic surgery and the postoperative neurocognitive function

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048645

Enrollment

Unknown

Registered

2021-07-12

Start date

2021-07-15

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

scoliosis

Interventions

test group:cerebral oxygen saturation goal-oriented anesthesia management

Control group:No

Eligibility

Sex/Gender

All

Age

12 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients who need spinal orthopedic surgery; 2. Basal blood pressure systolic blood pressure <180mmHg, diastolic blood pressure <110mmHg; 3. Age between 12 and 75 years old; 4. ASA classification I ~ II.

Exclusion criteria

Exclusion criteria: 1. Patients with obvious vital organ diseases; 2. Those with allergies; 3. Communication barriers and uncooperative persons; 4. Patients with preoperative anemia (hemoglobin (Hb)<=110 g/L); 5. Have a history of hearing impairment and epilepsy.

Design outcomes

Primary

Measure	Time frame
scale of the quality of wake-up test;wake-up time;cerebral oxygen saturation;incidence of postoperative cognitive disorders;anesthesia duration before wake-up test;mean arterial pressure (MAP);heart rate (HR);ramsay score during wake-up test;riker score during wake-up test;anesthesia recovery time;amount of hemorrhage;pulse oxygen saturation;digital pain rating scale;incidence of adverse effect;incidence of postoperative delirium;	—

Measure

Time frame

scale of the quality of wake-up test;wake-up time;cerebral oxygen saturation;incidence of postoperative cognitive disorders;anesthesia duration before wake-up test;mean arterial pressure (MAP);heart rate (HR);ramsay score during wake-up test;riker score during wake-up test;anesthesia recovery time;amount of hemorrhage;pulse oxygen saturation;digital pain rating scale;incidence of adverse effect;incidence of postoperative delirium;

—

Countries

China

Contacts

Public ContactGu Wei

Nanjing Drum Tower Hospital Anesthesiology Department

guwei9306@163.com+86 13851779306

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026