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Effects of timing of multimodal analgesia on pain duration and outcome after laparoscopic total hysterectomy

Effects of timing of multimodal analgesia on pain duration and outcome after laparoscopic total hysterectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048632
Enrollment
Unknown
Registered
2021-07-12
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign disease of uterus, Early uterine malignancy

Interventions

Completion group:30 minutes before the end of the operation, parecoxib sodium was instilled by rapid intravenous infusion, the dose reduction of remifentanil was started, and oxycodone 0.1 mg/kg was i
Before skin incision:30 minutes before skin incision, parecoxib sodium was instilled by rapid intravenous drip, 5-10 minutes before skin incision, oxycodone 0.1 mg/kg was intravenously administered, a

Sponsors

Xuanwu Hospital of Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification I ~ II; 2. Aged 18~65 years old; 3. Elective laparoscopic hysterectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. The trial involves contraindications to drug use; 2. Patients who routinely use opioids; 3. Drug addicts; 4. Patients with alcoholism; 5. Patients with vertigo; 6. Long-term constipation patients; 7. Patients with esophageal reflux; 8. Patients with diabetic neuropathic pain.

Design outcomes

Primary

MeasureTime frame
Duration of postoperative pain;

Secondary

MeasureTime frame
Frequency of side effects;Additional dose of analgesic drugs;Postoperative outcomes;VAS score at critical time points;

Countries

China

Contacts

Public ContactWang Tianlong

Miyun Hospital

w_tl5595@hotmail.com+86 13910525304

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026