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A medical records based study for effects of P2Y12 receptor antagonists on perioperative bleeding complications in patients undergoing off-pump coronary artery bypass grafting

Effects of P2Y12 receptor antagonists on perioperative bleeding complications in patients undergoing off-pump coronary artery bypass grafting

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048609
Enrollment
Unknown
Registered
2021-07-11
Start date
2021-07-07
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular disease

Interventions

Clopidogrel group:Stop clopidogrel for 5 days before surgery
Ticagrelor group:Stop ticagrelor for 5 days before surgery

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-85 years old; 2. Coronary heart disease with OPCABG surgery; 3. Receive aspirin combined with clopidogrel or ticagrelor before surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with other heart surgery; 2. Patients taking other antiplatelet drugs or anticoagulant drugs before surgery; 3. Patients with coagulation dysfunction or severe hepatic insufficiency or renal insufficiency; 4. Patients with severe systemic disease, such as severe infection and malignant tumor.

Design outcomes

Primary

MeasureTime frame
Severe postoperative bleeding;—

Countries

China

Contacts

Public ContactWang Zi

Zhongshan Hospital, Fudan University

18818263550@163.com+86 18818263550

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026