Clinical study of transcriptome-based diagnostic biomarker for acute febrile illness

Transcriptome-based diagnostic biomarker for acute febrile illness: a cross-sectional observational study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100048605

Enrollment

Unknown

Registered

2021-07-11

Start date

2021-09-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute febrile illness

Interventions

Gold Standard:Etiological evidence (culture, PCR, etc.) and confirmed by both clinical specialists

Index test:Measured expression of host gene transcripts by qRT-PCR

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Body temperature > 38 degree C; 2. The course of the disease is less than or equal to 14 days; 3. Subjects fully informed and agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Basic diseases that affect immune function, such as advanced tumors, autoimmune diseases, immunodeficiency patients, and immunosuppressive patients; 2. Pregnancy; 3. There are mixed infections (viral combined bacterial infection, autoimmune disease combined with bacterial infection); 4. Inability to provide complete clinical data; 5. Any situation in which the clinician believes that the patient should not participate in this study for safety reasons or the interests of the patient.

Design outcomes

Primary

Measure	Time frame
Accuracy;Sensitivity;Specificity;	—

Countries

China

Contacts

Public ContactWang Gang

Qilu Hospital of Shandong University

wangg1975@hotmail.com+86 18560082130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026