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Study on the relationship between intraoperative cerebral blood flow and postoperative neurocognitive dysfunction in elderly patients

Study on the relationship between intraoperative cerebral blood flow and postoperative neurocognitive dysfunction in elderly patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048599
Enrollment
Unknown
Registered
2021-07-11
Start date
2021-07-15
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative neurocognitive dysfunction

Interventions

Case group:Carotid ultrasound
control group:No

Sponsors

Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Elderly patients aged >= 65 years; 2. Plan elective general anesthesia surgery; 3. Types of surgery included: gastrointestinal surgery, gynecological surgery, lower extremity bone and joint surgery; 4. Patients voluntarily participated in this study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. A history of neurological and psychiatric diseases (including severe head trauma, patients with intracranial infection, Alzheimer's disease or other forms of dementia, and mental illness); 2. Preoperative neurological examination NIHSS > 4 points, imaging diagnosis of cerebral infarction, hemorrhage, tumor/inflammation, etc.; 3. Patients with delirium at the time of admission; 4. Patients with untreated diabetes, hypertension, coronary heart disease and other serious cardiovascular diseases; 5. There is alcohol dependence or withdrawal; 6. Patients who have been hospitalized within 3 months; 7. Patients with end-stage disease; 8. Patients with severe visual or hearing impairment that cannot be investigated.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;

Countries

China

Contacts

Public ContactWang E

Xiangya Hospital of Central South University

ewang324@163.com+86 18874889950

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026