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Effects of dexmedetomidine on postoperative cognitive function in elderly patients with asthenia

Effects of dexmedetomidine on postoperative cognitive function in elderly patients with asthenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048576
Enrollment
Unknown
Registered
2021-07-11
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive impairment

Interventions

Dexmedetomidine group:No
Control group:No

Sponsors

Tianjin Jinnan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing major laparoscopic abdominal surgery under elective general anesthesia (eg, gastrointestinal and gynecological surgery); 2. ASA classification II or III; 3. Gender is not limited; 4. Aged 60 to 75 years, height 155-180 cm, weight 50-75 kg; 5. The operation is expected to last for 2 hours or longer; 6. The patient has no severe hearing and visual impairment and can read.

Exclusion criteria

Exclusion criteria: 1. Serious diseases of cardiovascular, respiratory, liver, kidney or central nervous system, life expectancy is less than 3 months; 2. The score of simple mental state examination is less than 23 points; 3. A history of dementia or mental illness; 4. Current use of sedatives, antidepressants or corticosteroids; 5. Alcoholism and drug dependence; 6. Previously selected for this study; 7. Difficulty in follow-up or poor compliance; 8. Uncontrolled hypertension (over 180/100 mmHg).

Design outcomes

Primary

MeasureTime frame
postoperative cognitive impairment;—

Countries

China

Contacts

Public ContactNiu Tongxiang

Tianjin Jinnan Hospital

521i3@163.com+86 15122608987

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026