cesarean section under general anesthesia
Conditions
Interventions
Experimental group:Dexmedetomidine with Etomidate Fat Emulsion for Caesarean Section under General Anaesthesia
Control group:Routine induction under general anesthesia
Sponsors
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Eligibility
Sex/Gender
Female
Age
No minimum to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged <=40, female; 2. Full-term pregnant women receiving elective cesarean section under general anesthesia; 3. ASA classification is I or major grade; 4. Have a junior high school education; 5. Clearly understand and voluntarily participate in the study, and sign the informed consent by himself or his legal client.
Exclusion criteria
Exclusion criteria: 1. Allergic to dexmedetomidine, etomidate and other general anesthetic drugs; 2. Heart, lung, liver, kidney, nervous system or neuromuscular diseases, morbital obesity, diabetes, anemia, bleeding disorders, exposure to cardiovascular, antipsychotic or hypnotic medications, alcohol or drug abuse; 3. Maternal women with evidence of gestational hypertension, intrauterine growth restriction or fetal distress; 4. A history of drug abuse, drug abuse and alcoholism within 2 years prior to the screening period, with alcoholism being more than 2 units of alcohol per day on average (1 unit =360mL beer or 45mL liquor with 40% alcohol or 150mL wine); 5. Patients considered by the investigator to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure;Heart Rate;intraoperatve blood soss;Neonatal Apgar score;Neural Adaptability Score; | — |
Countries
China
Contacts
Public ContactHe Keqiang
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Outcome results
None listed