Effects of esketamine multimodal analgesia on postoperative analgesia and inflammation in patients undergoing artificial total knee arthroplasty

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048551

Enrollment

Unknown

Registered

2021-07-10

Start date

2021-07-05

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

artificial total knee arthroplasty

Interventions

Ket group :No

Control group:No

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meet the indications for total knee arthroplasty; 2. ASA I~II grade; 3. Aged 50 to 75 years; 4. BMI 18~30kg/?.

Exclusion criteria

Exclusion criteria: 1. The patient refuses to be included in the trial; 2. There is a history of allergy to related drugs; 3. The patient has a serious underlying disease; 4. Past mental or mental illness or cognitive impairment; 5. Suspected of abuse of alcohol or analgesic or sedative drugs.

Design outcomes

Primary

Measure	Time frame
patient controlled intravenousanalgesia press times;Sufentanil total dosage;Pain Numerical Scale;Time to remove the tracheal tube;Adverse reactions;Inflammatory factors;	—

Secondary

Measure	Time frame
Length of hospital stay;	—

Countries

China

Contacts

Public ContactZhao Lianghui

Xinxiang Central Hospital

327613059@qq.com+86 18841618050

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026