The screening and investigation of molecular mechanisms of genes susceptible to Noise induced deafness

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100048538

Enrollment

Unknown

Registered

2021-07-10

Start date

2021-07-01

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

noise-induced deafness

Interventions

case group:None

Control group:None

Eligibility

Sex/Gender

Male

Age

16 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 16 to 60 years; 2. Individual whose working hours exposed to occupational noise are not less than 1 year; 3. Individual who is ethnic Han.

Exclusion criteria

Exclusion criteria: 1.Individual who is currently suffering from hypertension, hyperlipidemia, diabetes or has a history of craniocerebral injury and otitis media; 2.Individual who has a history of use of ototoxic drugs or family history of hereditary deafness; 3.Individual whose hearing threshold difference of binaural high frequency air conduction is greater than 35dB.

Design outcomes

Primary

Measure	Time frame
Pure tone audiometry;genotype sequence;	—

Secondary

Measure	Time frame
otoacoustic emission;Questionnaire;	—

Countries

China

Contacts

Public ContactLu Lianjun

Tangdu Hospital, Air Force Medical University

lulianj@fmmu.edu.cn+86 29 84777446

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026