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Early effects of repetitive transcranial magnetic stimulation in combination with sertraline in adolescent patients with first-episode major depressive disorder

A randomized, double-blind, double-simulation, multi-center parallel controlled clinical study on the efficacy and safety of Zaoren Anshen Capsules combined with Zolpidem tartrate in the treatment of insomnia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048534
Enrollment
Unknown
Registered
2021-07-10
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adolescent depression

Interventions

Experimental group:repetitive transcranial magnetic stimulation

Sponsors

The First Clinical Medical College of Zhejiang University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for unipolar depressive disorder in the Diagnostic Statistical Manual of Mental Disorders Fourth Edition (DSM-IV); 2. Aged 12 to 18 years; 3. Han nationality, right-handed; 4. The first attack, never taking antidepressants, benzodiazepines and other antipsychotic drugs; 5. CDRS-R >= 40 points or HAMD-17 > 17 points.

Exclusion criteria

Exclusion criteria: 1. Suffering from mental retardation, substance dependence abuse, bipolar disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and eating disorder in accordance with DSM-IV; 2. Eliminate the history of serious physical disease and brain organic disease; 3. Previous epileptic seizures or abnormal EEG; 4. Exclude metal implants in the body.

Design outcomes

Primary

MeasureTime frame
Hamilton scale;Depression Rating Scale for Children - Revised Version;Audiovisual Integration Continuous Operations Test;THINC-it;

Countries

China

Contacts

Public ContactGao Jingfang

The First Clinical Medical College of Zhejiang University of Traditional Chinese Medicine

gjingfang@hotmail.com+86 13868012208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026