Lumbar stenosis
Conditions
Interventions
Experimental group:Fixed and then fused
The control group:Fused and then fixed
Sponsors
Shanghai Changzheng Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years; 2. Non-pregnant and lactating women; 3. The patient is suffering from lumbar spinal stenosis (refers to the clinical syndrome caused by nerve root and cauda equina nerve compression due to factors such as lumbar disc herniation or articular facet joint hyperplasia and stimulation, manifested as low back pain, lower extremity radiating pain, lower extremity numbness, lower extremity weakness, intermittent claudication, and even bowel and bladder dysfunction); 4. Diagnosis of lumbar spinal stenosis on lumbar spine imaging examinations (plain film, CT and MRI), caused by the compression of nerve tissue (spinal cord or nerve root) caused by herniated intervertebral disc or hyperplasia of facet joints, or the stenosis of nerve root outlet compression of nerve tissue; 5. Patients with obvious clinical symptoms of lumbar spinal stenosis, including low back pain, numbness and pain in lower limbs, intermittent claudication; physical examination patients with limited lumbar extension, positive or negative straight leg raising test, abnormal knee and tendon reflexes and other abnormal signs ; 6. Conservative treatment for more than 6 months, no significant improvement in symptoms, which seriously affects the patient's quality of life; 7. The patient has a strong willingness to accept surgery, and fully understands the differences and complications of the two surgical procedures in the clinical study, and signs the informed consent to voluntarily join the clinical trial.
Exclusion criteria
Exclusion criteria: 1.Complicated with cardiovascular, liver, kidney and hematopoietic system and other serious primary diseases, psychiatric patients and malignant diseases such as tumors; 2.Combined with congenital lumbar deformity, past history of infection, tumor history, trauma history, etc., resulting in obvious abnormal changes in the shape of the lumbar spine; 3.Presence of compression diseases in other parts of the spine except the lumbar spine, such as cervical intervertebral disc degenerative disease, cervical hyperextension injury, ossification of the posterior longitudinal ligament of the cervical spine, ossification of the posterior longitudinal ligament of the thoracic spine, ossification of the thoracic ligamentum flavum, etc; 4.There are other related diseases, such as piriformis syndrome, sciatic nerve injury, poliomyelitis, and Guillain-Barre syndrome, which affect nerve function and thus interfere with postoperative outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative neurological symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lumbar Japanese Orthopaedic Association Scores;pain score; | — |
Countries
China
Contacts
Public ContactGuo Yongfei
Shanghai Changzheng Hospital
Outcome results
None listed