Pathological study of paraspinal muscle biopsy in patients with scoliosis: a prospective study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100048484

Enrollment

Unknown

Registered

2021-07-09

Start date

2021-07-01

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal deformity

Interventions

Case group:Paraspinal muscle pathology

Control group:Paraspinal muscle pathology

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with scoliosis and lumbar disc herniation confirmed by clinical and imaging studies. 2. Scoliosis affects the quality of life or progresses rapidly and has a strong willingness to operate. 3. Patients who wish to explore and clarify the etiology of scoliosis.

Exclusion criteria

Exclusion criteria: 1. The purpose of admission treatment has nothing to do with scoliosis correction or lumbar disc herniation decompression and fusion. 2. Patients with severe comorbidities who cannot tolerate surgery. 3. Patients with inconsistent preoperative imaging and postoperative pathology.

Design outcomes

Primary

Measure	Time frame
Nash-moe type;Coronal Cobb angle;Lenke type;Expression of Dystrophin protein;Expression of MHC-1;	—

Secondary

Measure	Time frame
Other spine pelvis parameters;Pathological and morphological of Paravertebralmuscle;	—

Countries

China

Contacts

Public ContactYu Miao

Peking University Third Hospital

miltonyu@126.com+86 13601113284

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026