Analgesic effect of esmketamine on transversus abdominis plane block in laparoscopic inguinal hernia repair

Efficacy and safety of esketamine added to bupivacaine in transverse abdominis plane block for children undergoing laparoscopic inguinal hernia repair surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048483

Enrollment

Unknown

Registered

2021-07-09

Start date

2021-07-08

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pediatric hernia

Interventions

Group E:Bupivacaine combined with esketamine

Group B:Bupivacaine

Eligibility

Sex/Gender

All

Age

1 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 1-7 years, elective laparoscopic inguinal hernia repair; 2. Preoperative American Society of Anesthesiologists (ASA) grade I or II; 3. The patient's family members voluntarily participated in this trial and signed the informed consent.

Exclusion criteria

Exclusion criteria: Previous history of allergy to local anesthetics, contraindications to esketamine use, history of mental illness, long-term use of analgesics, preoperative liver and kidney insufficiency, and other systemic diseases.

Design outcomes

Secondary

Measure	Time frame
Intraoperative adverse reactions;Postoperative adverse reactions;	—

Primary

Measure	Time frame
Usage of analgesics during operation;Usage of postoperative analgesics;	—

Countries

China

Contacts

Public ContactWang Yanting

Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine

wyt_luna@hotmail.com+86 13816063223

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026