None listed
Conditions
Interventions
Group 1:Esketamine-Propofol
Group 2:Dexmedetomidine-Propofol
Sponsors
Children's Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
0.5 Years to 8 Years
Inclusion criteria
Inclusion criteria: 1. Aged 6 months to 8 years; 2. American Society of Anesthesiologists (ASA) grade I or II; 3. There are clear indications for 3T MRI examination under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Hemodynamic or respiratory instability; 2. Congenital heart disease with right-to-left shunt; 3. Increased intracranial pressure or increased intraocular pressure; 4. Cognitive impairment or abnormal behavior and spirit; 5. Have a history of general anesthesia for more than three times; 6. Allergic to the drugs involved in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total dose of propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Infusion dose of propofol;Incidence of upper airway obstruction;Incidence of oxygen desaturation;The incidence of bradycardia;Incidence of bradycardia requiring management;Time to recovery;Time to discharge; | — |
Countries
China
Contacts
Public ContactWang Qian
Children's Hospital of Soochow University
Outcome results
None listed