feeding intolerance in preterm infants
Conditions
Interventions
control group:Extensively hydrolyzed formulas
experimental group:Amino acid-based formula
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Admission between December 2021 and December 2023. 2. Gestational age (GA) < 32 weeks or birth weight < 1500g, appropriate for gestational age, admitted to Department of neonatology, Children's Hospital of Chongqing Medical University within the first 24 h after birth, maximal enteral intake <50mL/kg/day. 3. Receive milk for premature infants after admission; 4. Meet the diagnostic criteria of FI; 5. Children's guardians are willing to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Perinatal hypoxia; 2. History of underlying metabolic or chronic diseases, congenital malformations, or any other disease that may affect the ability to eat, normal growth and development, or participant assessment; 3. Major surgery requiring general anesthesia (except ligation of patent ductus arteriosus) was performed before or on the day of randomization; 4. Unstable blood pressure (allow 40% on the day of randomization (allowing nasal intubation and/or nasal continuous positive airway pressure (CPAP) and/or oxygen mask); 6. Diagnosis of grade III or IV intraventricular hemorrhage (IVH) before or on the day of randomization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time (days) to reach full eternal feedings; | — |
Countries
China
Contacts
Public ContactLu Qi
Children's Hospital of Chongqing Medical University
Outcome results
None listed