coronary artery disease
Conditions
Interventions
stable coronary heart disease group:none
unstable coronary heart disease group:none
Sponsors
The First Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Normal control: coronary angiography was completely normal, and carotid ultrasound showed no plaque. 2. Patients with stable coronary artery disease: clinical diagnosis of stable angina pectoris; coronary angiography showed obvious atherosclerotic lesions in the coronary artery (lumen diameter stenosis> 50%). 3. Patients with unstable coronary artery disease: clinical diagnosis of acute coronary syndrome; coronary angiography shows obvious coronary artery disease (luminal diameter stenosis>50%) (thrombosis is preferred); IVUS or OCT suggest unstable plaque is also acceptable.
Exclusion criteria
Exclusion criteria: 1. Aged <18 years; 2. Severe heart failure due to heart valve dysfunction and severe arrhythmia; 3. Combined with severe liver and kidney insufficiency; 4. Combined with malignant tumor; 5. Complicated or suspected of having systemic embolic diseases such as pulmonary embolism, severe lower extremity deep vein thrombosis, etc.; 6. Combined with severe autoimmune disease, acute exacerbation of chronic inflammation in the past 1 month, severe infection and other acute inflammation history in the past 1 month; 7. There is a history of surgical trauma or severe trauma in the past 1 month, including hemorrhagic diseases, cerebral infarction, etc.; 8. Have received percutaneous coronary angiography stent placement or surgical bypass surgery in the past; 9. Being pregnant and preparing for pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiovascular events;Left ventricular ejection fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricular diameter; | — |
Countries
China
Contacts
Public ContactGuo Xiaogang
The First Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed