Assessing the feasibility of a modified lumbar plexus block and comparing the postoperative analgesic efficacy of this technique with femoral nerve block for total knee arthroplasty

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048454

Enrollment

Unknown

Registered

2021-07-09

Start date

2020-07-01

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Group LS:Modified lumber plexus block combined with sciatic nerve block

Group FS:Femoral nerve block combined with sciatic nerve block

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients aged 18 years or older who underwent total knee arthroplasty for knee osteoarthritis and had an American Society of Anesthesiologists physical status classification of 1-3.

Exclusion criteria

Exclusion criteria: The exclusion criteria were psychiatric disorders, inability to cooperate or communicate in Chinese, chronic pain, ingestion of any pain medication, lower limb neuropathy, allergy to nonsteroidal anti-inflammatory drugs, renal failure, myocardial ischemia, cerebral infarction, liver injury, active gastric ulcer, and contra-indications to regional anesthesia (coagulopathy, local infection at the block site, and/or allergy to local anesthetic).

Design outcomes

Primary

Measure	Time frame
the onset time of pain after surgery;	—

Secondary

Measure	Time frame
time to first analgesic request;sufentanil consumption within 24 hours postoperatively;NRS score of rest pain;NRS scores for dynamic pain;Bromage score;Total intraoperative dose of sufentanil;the visibility scores of the nerves;the onset time of sensorial blockade;the pinprick sensation score 30minutes after injection;the sex, age, height, weight, affected side, American Society of Anesthesiologists grade, duration of surgery;dose of metoclopramide;	—

Measure

Time frame

time to first analgesic request;sufentanil consumption within 24 hours postoperatively;NRS score of rest pain;NRS scores for dynamic pain;Bromage score;Total intraoperative dose of sufentanil;the visibility scores of the nerves;the onset time of sensorial blockade;the pinprick sensation score 30minutes after injection;the sex, age, height, weight, affected side, American Society of Anesthesiologists grade, duration of surgery;dose of metoclopramide;

—

Countries

China

Contacts

Public ContactWen-Yi Gong

Wusong Hospital, Shanghai (Zhongshan Wusong Hospital Affiliated to Fudan University)

gong.wy@hotmail.com+86 13816983539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026