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Arandomised trial: Effects of different anesthesia methods on early perioperative pain sensitivity and cellular immune function in patients undergoing radical mastectomy

Arandomised trial: Effects of different anesthesia methods on early perioperative pain sensitivity and cellular immune function in patients undergoing radical mastectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048438
Enrollment
Unknown
Registered
2021-07-07
Start date
2019-01-01
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Experimental group:transversus thoracic muscle plane-pectoral nerves (TTP-PECS) block combined with propofol anesthesia

Sponsors

Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. have undergone a radical mastectomy for breast cancer (according to the American Association of Anesthesiologists (ASA), the surgery is divided into grades I, II); 2. be aged 45 to 70 years; 3. have correctly followed the doctors instructions and have an accurate understanding of the pain score; 4. have provided informed consent.

Exclusion criteria

Exclusion criteria: 1. had an organic disease; 2. had blood diseases and coagulation dysfunction; 3. allergic to anesthetics; 4. were infected at the puncture site; 5. had central or peripheral nervous system diseases; 6. and/or had a long-term history of receiving analgesic and sedative medications.

Design outcomes

Primary

MeasureTime frame
Pain score, hemodynamic indicators, cellular immunity, wake-up time and incidence of adverse reactions in the two groups;

Countries

China

Contacts

Public ContactDu Yu

Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China

duyu2011@163.com+86 15902841202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026