Acute ischemic stroke
Conditions
Interventions
observation group:pentoxifylline sustained-release tablets
control group:the guidelines for acute ischemic stroke recommend medication
Sponsors
Seventh Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Aged from 40 to 85 years; (2) Conformed to the diagnosis of acute ischemic stroke, confirmed by cranial CT or MRI examination, accompanied by dizziness /Vertigo, onset of 24h to within 7 days; (3) NIHSS score <=5 points.
Exclusion criteria
Exclusion criteria: (1) Exclude other peripheral vertigo such as benign paroxygenic positional vertigo; (2) Intracerebral hemorrhage, subarachnoid hemorrhage, hemorrhagic cerebral infarction, intracranial abnormal vascular network disease, brain tumor, tumor Stroke; (3) Patients with heart, liver, kidney, hematopoietic system and other serious primary diseases, in which ALT>=2.5 ULN; AST>=2.5 ULN, Cre >=1.5 ULN; (4) Pregnant or lactating women; (5) People with known allergic history to hexantheobromine, methylxanthine and basic therapeutic drugs; (6) Hypotension syndrome, systolic blood pressure <=110mmHg and diastolic blood pressure <=60mmHg; (7) Joint deformity affecting functional recovery; (8) gastrointestinal bleeding or ulcers, or nasal feeding can not take oral drugs and patients with definite bleeding tendency, long-term use anticoagulants (e.g., warfarin); (9) Other life-threatening or serious diseases with an expected survival period of less than 12 months; (10) Other disorders or psychiatric conditions that the investigator believes may limit neurological evaluation or patient follow-up; (11) Patients enrolled in other clinical trials within 30 days; (12) Other similar vasodilators were combined.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DARS; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS;mRS; | — |
Countries
China
Contacts
Public ContactZhang Weiwei
The Seventh Medical Center of PLA General Hospital
Outcome results
None listed