Establish a continuous monitoring system for intestinal markers to guide and evaluate the implementation of enteral nutrition in patients with acute gastrointestinal injury (AGI) in ICU

Intestinal markers guide the implementation of enteral nutrition for patients with acute gastrointestinal injury (AGI) in ICU

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100048398

Enrollment

Unknown

Registered

2021-07-06

Start date

2021-06-30

Completion date

Unknown

Last updated

2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Gastrointestinal Injury (AGI)

Interventions

AGI class II group:None

AGI class III group:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Older than 18 years old; 2.APACHE score >8; 3.Expect to stay in ICU for more than one week; 4.Hemodynamic stability (mean arterial pressure >=65mmHg) can be maintained for 6h with the support of vasoactive drugs (including dopamine, norepinephrine, epinephrine, phenoxyrepinephrine and vasopressin); 5.AGI II-III grade.

Exclusion criteria

Exclusion criteria: 1.Pregnant women, patients near death, or patients with failed fluid resuscitation; 2.End-stage patients with multiple organ failure; 3.Patients with malignant tumor; 4.Intestinal primary diseases (intestinal obstruction, gastrointestinal bleeding, etc.) and postoperative intestinal surgery; 5.Patients died during the observation period (within 7 days).

Design outcomes

Primary

Measure	Time frame
D-lactic acid;Intestinal fatty acid binding protein;Citrulline;	—

Countries

China

Contacts

Public ContactLu Jian

The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital)

382139777@qq.com+86 13913103133

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026