Myasthenia gravis
Conditions
Interventions
Sponsors
The Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age is not limited, gender is not limited; 2.Clinical MG manifestations, and or neostigmine test positive, low frequency repeated electrical stimulation positive, serum AChR, Musk, LRP4, Titin, RyR and other antibodies are positive, clinical diagnosis of myasthenia gravis can be diagnosed; 3.Patients with myasthenia gravis classified as type I, type II (type IIa, type IIb), III (type IIIa, type IIIb) and IV (type IVa, IVb) in clinical MGFA; 4.Agree to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with severe medical diseases: severe arrhythmia, severe lung disease, ALT/AST> 2 times the normal value, Cr> 2 times the normal value; 2.Patients with malignant tumors (excluding thymoma), history of HIV infection, or severe immunodeficiency; 3.Female patients who are pregnant, breastfeeding or breastfeeding; 4.History of mental illness; 5.Tuberculosis patients with tuberculin test or T-SPOT test positive.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantitative myasthenia gravis score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Myasthenia Gravis Daily Living Scale;Myasthenia Gravis Quality of Life Scale;Myasthenia gravis specific muscle strength test;Absolute and relative scores for myasthenia gravis;Analysis of the dosage of other drugs such as cholinesterase inhibitors, glucocorticoids, immunosuppressants, etc.;Acetylcholine receptor antibody quantitative value;Security Index; | — |
Countries
China
Contacts
Public ContactWang Jian
The Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Outcome results
None listed