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The role of ultrasound super-resolution microcirculation imaging in the diagnosis, treatment and prognostic evaluation of muli-organ tumors and diseases related to microcirculation disorders in a multi-center joint study

The role of ultrasound super-resolution microcirculation imaging in the diagnosis, treatment and prognostic evaluation of muli-organ tumors and diseases related to microcirculation disorders in a multi-center joint study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048361
Enrollment
Unknown
Registered
2021-07-06
Start date
2021-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tumors and diseases related to microcirculation disorders

Interventions

Index test:ultrasound super-resolution microcirculation imaging: 1. qualitative parameters

Sponsors

Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing contrast-enhanced ultrasound and histologically or clinically proven tumors of muli-organ and disorders related to microcirculation; 2. Microbubbles should be distributed individually; 3. Aged 18 to 75 years, no gender preference; 4. Patients volunteer to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Poor quality of dynamic contrast-enhanced ultrasound images. 2. Large tissue motions; 3. The frame rate is too low in contrast mode; 4. More than 3 months for the time interval between CEUS and histological results.

Design outcomes

Primary

MeasureTime frame
The differences in the qualitative parameters for the differential diagnosis;

Secondary

MeasureTime frame
The differences in the quantitative parameters for the differential diagnosis;Diagnostic performances of qualitative parameters ;Diagnostic performances of quantitative parameters ;Relationships between the qualitative parameters and histologic biomarkers ;Relationships between the quantitative parameters and histologic biomarkers ;The evaluation of inter-reader and intra-reader reproducibility;Relationships between the qualitative parameters and histologic biomarkers ;Relationships between the quantitative parameters and histologic biomarkers ;The evaluation of inter-reader and intra-reader reproducibility;

Countries

China

Contacts

Public ContactZheng Yuanyi

Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

zhengyuanyi@163.com+86 189 3017 7162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 23, 2026