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Prospective clinical study on the efficacy and safety of in vivo ovarian activation combined with ovarian tissue cryopreservation for fertility preservation in patients with premature ovarian insufficiency

Prospective clinical study on the efficacy and safety of in vivo ovarian activation combined with ovarian tissue cryopreservation for fertility preservation in patients with premature ovarian insufficiency

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048352
Enrollment
Unknown
Registered
2021-07-06
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature ovarian failure

Interventions

Case series:Ovarian tissue activation

Sponsors

Obstetrics and Gynecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 40 Years

Inclusion criteria

Inclusion criteria: 1.The preservation of fertility is strongly required; 2.Aged 25; AMH<0.5ng/ml); 4.Can tolerate laparoscopic surgery; 5.Subjects voluntarily participate in this study, sign informed consent, good compliance, and cooperate with follow-up.

Exclusion criteria

Exclusion criteria: 1.Patients with ovarian tumor involvement or high risk of ovarian metastasis; 2.Patients with infectious diseases (HIV, syphilis, hepatitis, etc.; 3.Patients with surgery or anesthesia contraindication; 4.Patients with mental disorders or a clear family history of mental diseases; 5.Tumor gene test results suggest germ-line pathogenic variation.

Design outcomes

Primary

MeasureTime frame
endocrine;pregnancy;—

Countries

China

Contacts

Public ContactXu Congjian

Obstetrics and Gynecology Hospital of Fudan University

xucongjian1275@fckyy.org.cn+86 13651796353

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026