Postoperative sedation
Conditions
Interventions
Dexmedetomidine group:Dexmedetomidine
Sponsors
Peking University Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 80 years (exclude 80); 2.Patients who planned to undergo elective maxillofacial surgery for mass resection and free tissue flap repair; 3.Postoperative preventive tracheotomy was not performed, and endotracheal intubation was retained; 4.Voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with bradycardia before surgery (ecg heart rate = grade IV; 7.Known allergy to a2 agonists, rimazolam, or other benzodiazepines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of posoperative agitation in post-anesthesia care unit (PACU); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of delirium within the first 5 days after surgery;Severity of pain at postoperative 6, 12, 24 h;Incidence of postoperative nausea and vomiting;Length of stay in hospital after surgery;Incidence of in-hospital other complications and all-cause in-hospital mortality after surgery; | — |
Countries
China
Contacts
Public ContactYang Xudong
Peking University Hospital of Stomatology
Outcome results
None listed