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The effect of preoperative preventive use of antibiotics on the surgical site infection in patients with chronic appendicitis after laparoscopic appendectomy

The effect of preoperative preventive use of antibiotics on the surgical site infection in patients with chronic appendicitis after laparoscopic appendectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048336
Enrollment
Unknown
Registered
2021-07-05
Start date
2021-07-15
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic appendicitis

Interventions

Test group:No antibiotics before surgery
Control group:None

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Aged 14 to 70 years, and the condition meets the clinically prescribed diagnostic criteria for chronic appendicitis; 2.Indications for surgical treatment; 3.No history of acute attack within 1 month; 4.There is no obvious abnormality in the function of important organs, no comorbidity of the heart or lung and other organs, and the classification of the American Society of Anesthesiologists is less than 3; 5.Signed an informed consent form for this study voluntarily.

Exclusion criteria

Exclusion criteria: 1.Antibiotics have been used for treatment within 1 week before surgery; 2.Glucocorticoids have been used for treatment within 3 months before surgery; 3.Combined immunodeficiency disease, bleeding disease or bacterial infectious disease; 4.There is infection of other parts before operation; 5.Preoperative blood routine, CRP, body temperature and other related indicators suggest infection; 6.During the operation, it was found that the appendix had empyema, the appendix was ruptured, and the operation time was more than 3 hours.

Design outcomes

Primary

MeasureTime frame
Surgery site infection;

Countries

China

Contacts

Public ContactWang Haibin

Affiliated Hospital of Guizhou Medical University

wanghb988@163.com+86 13595005192

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026