Helicobacter pylori infection
Conditions
Interventions
Control group:Bismuth Potassium Citrate Capsules 0.6g bid+ Esomeprazole Magnesium Enteric-coated Tablets 20mg bid +Amoxicillin Capsules 1g bid+ Clarithromycin Sustained Release Tablets 500mg bid, oral
Treatment group:Bismuth Potassium Citrate Capsules 0.6g bid + Esomeprazole Magnesium Enteric-coated Tablets 20mg bid +Amoxicillin Capsules 1g bid +Minocycline Hydrochloride Capsules 100mg bid, orally
Sponsors
Suzhou Dushu Lake Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.13 or 14 carbon-urea breath test positive; 2.Never received Hp eradication therapy; 3.Aged 18 to 70 years, no gender limitation.
Exclusion criteria
Exclusion criteria: 1.Women during gestation or lactation period; 2.Continuous use of bismuth or proton-pump inhibitors within 2 weeks before enrollment; 3.Continuous use of antibiotics within 1 weeks before enrollment; 4.History of acute gastrointestinal bleeding within 1 weeks before enrollment; 5.History of malignant tumor of upper gastrointestinal tract; 6.History of surgery of upper gastrointestinal tract causing changes of gastric anatomy; 7.History of insufficiency of heart, lung, liver or kidneys; 8.Allergy to any drugs involved in this research; 9.History of participation in other drug clinical trials within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complicance;Safety; | — |
Countries
China
Contacts
Public ContactJiang Caifeng
Suzhou Dushu Lake Hospital
Outcome results
None listed