frailty
Conditions
Interventions
Intervention group:Vitamin D3 combined with exercise
Control group:Health education
Sponsors
Shengjing Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Residents aged 65 and over in Northeast China; 2.Less than 3 hours of physical activity per week; 3.Patients diagnosed as weak or pre-weak according to weak index (FI) (see Appendix 2); 4.No medical contraindications for strength training; 5.Being able to walk (without a walker); 6.Chronic diseases which are stable for more than 6 months after reasonable treatment; 7.Sign informed consent form.
Exclusion criteria
Exclusion criteria: 1.Auditory/visual impairment affecting daily activities; 2.Patients with malignant tumors who are currently undergoing or plan to undergo chemotherapy or radiotherapy; 3.Medication history: patients who took calcium or vitamin D supplements and sedative, antidepressant and anxiolytic drugs; 4.Respiratory failure, heart failure, severe liver and kidney dysfunction; 5.Patients with acute phase of the disease (infection, fever, etc.); 6.Diagnosis of malnutrition; 7.Life expectancy for any reason is less than 12 months; 8.Persons with physical and mental disabilities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frailty assessment;physical performence;quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| muscle mass;muscle strength;bone density;inflammatory factor; | — |
Countries
China
Contacts
Public ContactWang Difei
Shengjing Hospital of China Medical University
Outcome results
None listed