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Randomized controlled trial of using Diane-35 downregulation in assisted reproductive technology

Randomized controlled trial of using Diane-35 downregulation in assisted reproductive technology

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048310
Enrollment
Unknown
Registered
2021-07-05
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Experimental group:Diane-35 downregulation
Control group:GnRH downregulation

Sponsors

Center of Reproductive Medicine, Children's Hospital of Shanxi and Women Health Center of Shanxi
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 35 Years

Inclusion criteria

Inclusion criteria: Select infertile patients receiving IVF-ET treatment at our Reproductive Medicine Center.The patients were qualified to be enrolled in the study who should meet the following criteria are included: 1.Never had any IVF/ICSI cycles before; 2.Age no older than 35; 3.Ovarian reserve function is normal (basal serum follicle-stimulating hormone (FSH) concentration of lower than 15 U/L on the day 2-4 of menstruation). Patients treated with the contraceptive drug Eynestradiol cyproterone tablet (Diane-35) were in the control group and those treated with the standard long regimen of traditional gonadotropin-releasing hormone inhibitor were in the control group.

Exclusion criteria

Exclusion criteria: 1.Polycystic ovary syndrome; 2.Endometriosis Grade I or above; 3.Congenital abnormal uterine development; 4.Have received hormone therapy in the past 1 month.

Design outcomes

Primary

MeasureTime frame
Implantation rate;Clinical pregnancy rate;

Secondary

MeasureTime frame
Gonadotropin priming day follicle stimulating hormone;Serum luteinizing hormone on gonadotropin initiation day;Gonadotropin initiation day estradiol;Gonadotropin primes progesterone;Gonadotropin dosage;Days of gonadotropin medication;Number of follicles >14mm in diameter;Retrieved oocyte number ;Number of mature oocyte;Normally fertilized oocyte;Good quality embryos number;Viable embryos number;

Countries

China

Contacts

Public ContactBi Xingyu

Center of Reproductive Medicine, Children's Hospital of Shanxi and Women Health Center of Shanxi

75790288@qq.com+86 13934152277

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026