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Clinical study of fresh Chinese olive on xerostomia in patients with maintenance peritoneal dialysis

Clinical study of fresh Chinese olive on xerostomia in patients with maintenance peritoneal dialysis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048308
Enrollment
Unknown
Registered
2021-07-05
Start date
2020-07-01
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xerostomia in peritoneal dialysis patients

Interventions

Goup A:conventional treatment
Goup B:conventional treatment+Chew fresh olive

Sponsors

Guangdong Provincial Hospital of Chinese Medicine,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. diagnostic criteria for end-stage renal disease; 2. aged 25-80 years old; 3. maintain regular peritoneal dialysis for more than 3 months and stable condition; 4. xerostomia and lasted more than 1 months; 5. clear consciousness, good compliance, no history of mental illness, and able to cooperate in collecting clinical data; 6. signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. patients who are allergic to olives or refuse to participate in the study; have swallowing disorders; 2. patients with peritoneal dialysis combined with hemodialysis; 3. patients whose tooth defect seriously affects chewing function; 4. exclude Sjogren's syndrome and other salivary gland organic diseases; hyperkalemia; a history of obvious symptoms of peptic ulcer in the past 1 month; a history of cardiovascular and cerebrovascular accidents, severe infections, and acute gastrointestinal hemorrhage in the past 3 months.

Design outcomes

Primary

MeasureTime frame
SXI, VAS;

Secondary

MeasureTime frame
Blood pressure changes;BMI;Saliva Ph;Peritoneal dialysis prescription related index change value;

Countries

China

Contacts

Public ContactWei Feiyuan

Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

feiyuan_wei@163.com+86 13435694094

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026