Comparative analysis of calcium free dialysate and calcium containing dialysate in continuous renal replacement therapy with citrate anticoagulation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048238

Enrollment

Unknown

Registered

2021-07-05

Start date

2021-07-05

Completion date

Unknown

Last updated

2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:CVVHD mode with calcium-free dialysate

Group 2:CVVHDF mode with calcium-free dialysate

Group 3:CVVHDF mode, using calcium-containing dialysate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: CRRT treatment indications must be met (one of which is met): severe congestive heart failure, severe acid-base imbalance and electrolyte disturbance, acute kidney injury (AKI) stage 2-3, perioperative prevention of contrast-induced nephropathy , combined with extracorporeal membrane oxygenation (ECMO).

Exclusion criteria

Exclusion criteria: Severe liver dysfunction (Child-Pugh C), refractory hypoxemia (PO22.8mmol/L), hypernatremia (serum sodium>150mmol/L), metabolic alkalosis (HCO3->27mmol/L).

Design outcomes

Primary

Measure	Time frame
blood gas analysis;biochemical detection;coagulation function;routine blood test;arterial pressure, venous pressure, transmembrane pressure of CRRT machine;filter thrombus classification;	—

Countries

China

Contacts

Public ContactMeng Fanqi

Xiamen Cardiovascular Hospital, Xiamen University

mengfanqi19831001@163.com+86 15959232882

Outcome results