pulmonary nodules
Conditions
Interventions
Control group:Placebo
Sponsors
Weihai Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years old; 2. Pulmonary nodules (pure ground-glass nodules or mixed nodules with ground-glass components, diameter 5-8mm) diagnosed by thin-layer lung CT within 1 month; high-risk nodules of lung cancer were analyzed by AI; 3. Pulmonary nodules have been diagnosed and treated by specialists, and no further diagnosis and treatment are currently required. It is recommended to follow up observers; 4. Informed and voluntarily participated in the study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women; 2. Patients with unstable vital signs and unstable condition; 3. The pulmonary nodule is a solid nodule; or the nodule is less than 4mm and larger than 8mm; or after the diagnosis and treatment of a specialist, it is recommended to conduct further diagnosis and treatment immediately; 4. CT showed imaging manifestations of other pulmonary diseases besides pulmonary nodules; 5. Combined with serious primary diseases such as active malignant tumor, cerebral apoplexy, myocardial infarction; 6. Patients with a history of gastrointestinal bleeding, irritable bowel syndrome, Crohn's disease or ulcerative colitis and other gastrointestinal diseases, and a history of gastrointestinal surgery; 7. Patients with a history of mental illness; 8. Patients who have taken antibiotics, glucocorticoids or other immunosuppressive agents, foods and medicines containing probiotics and prebiotics within the past 1 month; 9. Those who are allergic to the test sample or have obvious gastrointestinal symptoms such as intolerance; 10. Patients receiving other clinical trials at the same time; 11. The researcher cannot be completed on time as determined by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nodule diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety Scale score;Lymphocyte subsets;Metagenome sequencing of intestinal flora; | — |
Countries
China
Contacts
Public ContactLiu Ailing
Weihai Municipal Hospital
Outcome results
None listed