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Establishment and validation of a short-term prognostic risk model for AIDS patients with pneumocystis pneumonia

Establishment and validation of a short-term prognostic risk model for AIDS patients with pneumocystis pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048218
Enrollment
Unknown
Registered
2021-07-05
Start date
2021-06-30
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AIDS complicated with pneumocystis pneumonia

Interventions

Gold Standard:Clinical outcome
Index test:predictionary model

Sponsors

Beijing You'an Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The diagnostic criteria of AIDS and PCP refer to the diagnostic criteria of the AIDS and Hepatitis C Group of the Infectious Diseases Branch of the Chinese Medical Association and the Chinese AIDS Diagnosis and Treatment Guidelines (2018 Edition) of the Chinese Center for Disease Control and Prevention. 2. All patients were confirmed to be positive for anti-HIV-1 antibody by enzyme-linked immunosorbent assay (ELISA) primary screening and Western blotting test (WB). 3. The diagnostic criteria for PCP are: (1) Insidious or subacute onset, dry cough, shortness of breath and aggravation after exercise, may have fever, cyanosis, and respiratory distress in severe cases; (2) There are few positive signs in the lungs, or a small amount of scattered dry and wet rales can be heard. Signs are often disproportionate to the severity of disease symptoms; (3) Chest X-ray examination: diffuse reticular nodular interstitial infiltration from the hilum of both lungs, sometimes with ground-glass opacity; (4) Blood gas analysis showed hypoxemia; (5) Blood lactate dehydrogenase is often elevated; (6) Diagnosis depends on pathogenic examinations such as sputum or bronchoalveolar lavage/lung biopsy to find cysts or trophozoites of Pneumocystis carinii.

Exclusion criteria

Exclusion criteria: Patients with unobserved clinical outcomes and incomplete clinical data were automatically discharged from hospital.

Design outcomes

Primary

MeasureTime frame
Clinical outcome;

Countries

China

Contacts

Public ContactLi Aixin

Beijing You'an Hospital, Capital Medical University

liaixin8194@sina.com+86 13264161606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026