Uncomplicated Acute Appendicitis
Conditions
Interventions
Group A:ERAT combined with antibiotic therapy
Group B:Conservative treatment with antibiotics alone
Sponsors
First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years, gender is not limited. 2. Clinical manifestations of UCAA (acute uncomplicated appendicitis): (1) Clinical manifestations combined with acute appendicitis (symptoms + signs + laboratory test results, that is, Alvarado score >= 5); (2) CT or color Doppler ultrasound conforms to UCAA: 1) The appendix is visible in shape, with an inner diameter of 6-15mm; 2) and/or: fat streak sign around the appendix; calculi and gas shadows in the appendix; thickening of the intestinal wall around the appendix (cecum>4mm/ileum>2mm); 3) Exclude any one of the following: fluid around the appendix; ascites; gas shadow outside the appendix; causing suppurative portal phlebitis. 3. No mental illness.
Exclusion criteria
Exclusion criteria: 1. Refuse to sign the informed consent; 2. History of IBD; 3. Pregnant and lactating women; 4. Long-term hormone, anticoagulant therapy, severe bleeding tendency; 5. Severe cardiovascular and cerebrovascular diseases, severe abnormal liver and kidney functions, and mental disorders; 6. Life expectancy < 6 months / those who cannot complete the follow-up process for more than 6 months; 7. CT clearly indicates acute perforated appendicitis/periappendiceal abscess/peritonitis; 8. Those who have been included in other studies and have an influence on this study; 9. There are contraindications to CT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of post-treated pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical expenses (including lost income from absenteeism);Duration of absence from work and sports;Pain medication requirements;Hospital stay;The overall complication rate;Recurrent appendicitis rate;Types and times of antibiotics used;Time for inflammation indicators to return to normal;Stent implantation;Discharge without symptom relief rate; | — |
Countries
China
Contacts
Public ContactKong Lingjian
First Affiliated Hospital of Zhengzhou University
Outcome results
None listed