Preventive effect and mechanism of femoral artery block on tourniquet-related complications

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048203

Enrollment

Unknown

Registered

2021-07-04

Start date

2021-07-10

Completion date

Unknown

Last updated

2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group A:Ultrasound-guided peripheral nerve block (gluteal sciatica + femoral nerve block + adductor canal block) + femoral artery intrathecal block

Group B:Ultrasound-guided peripheral nerve block (gluteal sciatica + femoral nerve block + adductor canal block)

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-64 years; 2. ASA classification I-II; 3. BMI 18-26kg/m^2; 4. There was no obvious abnormality in preoperative cardiopulmonary function.

Exclusion criteria

Exclusion criteria: 1. The patient refuses to participate in the study; 2. Chronic pain requires long-term opioid use (more than 3 months) and a history of drug abuse; 3. Deep vein thrombosis; 4. History of local anesthetic allergy; 5. Inability to perform nerve block and contraindications of nerve block; 6. Tourniquet usage time is less than 60 minutes, or more than 90 minutes.

Design outcomes

Primary

Measure	Time frame
the occurrence of tourniquet-induced pain;	—

Secondary

Measure	Time frame
haemodynamics;total amount of midazolam, fentanyl and esmolol used during operation;malondialdehyde;catecholamines;superoxide dismutase;blood gas analysis;	—

Countries

China

Contacts

Public ContactNi Yan

The First Affiliated Hospital with Nanjing Medical University

niyan812@163.com+86 13913844476

Outcome results