colorectal cancer ,sarcopenia
Conditions
Interventions
Experimental group:ß- hydroxy- ß- methyl butyrate
Control Group:No
Sponsors
Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosed with colorectal cancer at the Affiliated Hospital of Southwest Medical University; 2. Has undergone surgical treatment; 3. Patients diagnosed with sarcopenia according to the 2019 AWGC consensus criteria.
Exclusion criteria
Exclusion criteria: 1. Spine and limb bone and joint diseases (such as ankylosing spondylitis, rheumatoid arthritis); 2. Patients with chronic cardiac insufficiency (refers to being unable to carry out normal daily activities: the heart failure is graded as iii or iv, or cannot tolerate a 6-m walking test); 3. Severe renal insufficiency and need to limit protein intake; 4. Poor compliance, unable to strictly abide by the doctor's orders; 5. Those with cognitive impairment and mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skeletal muscle index;tumor necrosis factor-like weak apoptosis-inducing factor;peroxisome proliferator-activated receptor coactivator 1-a;growth differentiation factor 15;grip strength;pace;leg circumference; | — |
Countries
China
Contacts
Public ContactWang Min
Affiliated Hospital of Southwest Medical University
Outcome results
None listed