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Effect of immediate ruduction in nicotine content of cigarettes vs re-consolidation time window combined with immediate ruduction in nicotine content of cigarettes on Smoke behaviors in patients with COPD

Effect of immediate ruduction in nicotine content of cigarettes vs re-consolidation time window combined with immediate ruduction in nicotine content of cigarettes on Smoke behaviors in patients with COPD

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048158
Enrollment
Unknown
Registered
2021-07-04
Start date
2021-07-10
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addictive substance use disorder

Interventions

Experimental group1:Smoke cigarettes with very low nicotine content
Experimental group2:Re-consolidation time window combined with immediate reduction to 0.1 mg nicotine content
Control Group:No

Sponsors

Institute of Psychology, Chinese Academy of Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged > 18 years old; 2. Daily smoking (5 cigarettes per day on average for at least 1 year, no smoking cessation attempt (more than 3 days) in the past 30 days); 3. Patients diagnosed with chronic obstructive pulmonary disease; 4. No unstable medical or psychiatric conditions.

Exclusion criteria

Exclusion criteria: 1. Deterioration of mental symptoms or physiological state due to drug changes; 2. Frequent use of tobacco other than cigarettes; 3. Currently using nicotine substitutes or other tobacco products to quit smoking; 4. Pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
cigarette per day;craving;emotion;—

Secondary

MeasureTime frame
Nicotine dependence;withdrawal;Self Rating anxiety scale/SAS;Self-rating depression scale/SDS;urges;—

Countries

China

Contacts

Public ContactLi Yonghui

Institute of Psychology, Chinese Academy of Sciences

liyonghui@psych.ac.cn+86 18612635067

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026