epilepsy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with epilepsy according to the criteria proposed by the International Anti-Epilepsy Union in 2017; 2. Aged 18 to 65 years; 3. Patients did not have seizures 6 months before vaccination 4. Patients and their family members gave informed consent to participate in this study voluntarily.
Exclusion criteria
Exclusion criteria: 1. Have a clear history of vaccine-induced seizures or exacerbation of seizures; 2. Four weeks before inoculation, the frequency of seizures in basal line stage was frequent, or there was epileptic status; 3. lactating women or pregnant women; 4. Have a history of other medical diseases and mental illness; 5. Severe liver and kidney dysfunction or severe infection; 6. known history of alcohol or drug addiction or abuse; 7. People with allergy; 8. Patients and their families refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of seizures after vaccination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions;Result of electroencephalogram; | — |
Countries
China
Contacts
Qilu Hospital, Shandong University