Skip to content

Clinical study on the treatment of knee osteoarthritis by intra-articular injection of ''triple needle''

Clinical study on the treatment of knee osteoarthritis by intra-articular injection of ''triple needle''

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048131
Enrollment
Unknown
Registered
2021-07-04
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee

Interventions

Experimental group:triple needle

Sponsors

The People's Hospital of Guangxi Zhuang Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 70 years; 2. Unilateral knee pain or swelling symptoms have existed for at least 6 months, and the contralateral side has no obvious clinical symptoms; 3. Imaging evidence: knee X-rays suggest stage ii-iv knee osteoarthritis (K-L score); 4. Intolerance or poor response to drugs such as NSAIDs; 5. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those with abnormal rheumatic immune indexes; 2. Joint ligament injury caused instability or previous trauma; 3. Those with loose bodies and meniscus injuries causing joint interlocking; 4. Patellofemoral arthritis-based knee osteoarthritis; 5. Had intra-articular viscoelastic agent supplementary therapy (injected chondroprotective agent or sodium hyaluronate) or intra-articular or systemic injection of glucocorticoid or oral analgesics within 3 days within 6 months; 6. History of knee surgery or physical therapy within the previous 6 months; 7. Combined with cardiovascular and cerebrovascular diseases, infections, immunosuppression, severe diabetes and other diseases; 8. Patients lost to follow-up or unable to complete the treatment cycle.

Design outcomes

Primary

MeasureTime frame
The Western Ontario and McMaster Universities score of knee joint;

Countries

China

Contacts

Public ContactYin Dong

The People's Hospital of Guangxi Zhuang Autonomous Region/Guangxi Academy of Medical Sciences

tangin2002@163.com+86 7712186567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026