Febrile Neutropenia
Conditions
Interventions
Sponsors
Shanxi Tumor Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with HL or NHL who received at least one cycle of chemotherapy were enrolled. All patients signed informed consent forms. Aged >=18 years; the ability to complete at least one cycle of chemotherapy as planned (patients with an intermediate risk of FN needed to have more than one risk factor); a normal bone marrow hematopoietic function with no bleeding tendency; absolute neutrophil count (ANC) >=2.0x10^9/L, serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) <=1.5 ULN, serum total bilirubin (TBIL) <=1.5 ULN, serum creatinine (Scr) <=1.5 ULN.
Exclusion criteria
Exclusion criteria: Presence of acute infection and receipt of systemic anti-infection treatment in the 72 hours before chemotherapy; presence of hematological diseases affecting the hematopoietic function of bone marrow; patients who had bone marrow or stem-cell transplantation within the past 3 months; presence of other uncured or brain metastatic malignant tumors; presence of allergic reaction or intolerance to the study drugs; presence of mental or nervous system disorders; women who were pregnant or breast feeding; women of childbearing age who refused contraceptive use; patients who had previously received PEG-rhG-CSF; and some special cases that the investigators determined should be excluded.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Biochemicaltests; | — |
Primary
| Measure | Time frame |
|---|---|
| ANC; | — |
Countries
China
Contacts
Public ContactSu Liping
Shanxi Tumor Hospital
Outcome results
None listed