Obesity
Conditions
Interventions
Placebo group:Maltodextrin (13.8g)
Alginates group:Alginates (15g)
Sponsors
Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 18-35 year; 2. BMI 24-28.
Exclusion criteria
Exclusion criteria: Current acute or chronic diseases (including metabolic diseases, liver and kidney disorders, gastrointestinal diseases, cardiovascular diseases), excessive psychiatric diseases and any infectious disease; History of bariatric or gastrointestinal surgery, received other operation treatment in the prior 3 months or a plan to accept surgery in 3 months; Smoking excessive drinking (>2 glasses/day); Extreme exercise activity (>10 h/week); Taken dietary supplement in the last 3 months (including omega-3 fatty acids, prebiotics, probiotic, plant sterols/steroids ), long-term dietary fiber >30 g/d; Vegetarian or other unusual diets; Use of medicine (including antibiotics, glucocorticoids, immunosuppressive drugs, statins, fibrates, orlistat, ezetimibe) in the previous 3 months; Over 3 kg weight change in last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition (bioelectric impedance); | — |
Secondary
| Measure | Time frame |
|---|---|
| Triglyceride;Total cholesterol;High-density lipoprotein;Low-density lipoprotein;Fasting blood glucose;Peptide YY;Insulin;Gut microbiota;Short chain fatty acids of feces;Tumour necrosis factor-alpha;Monocyte chemoattractant protein-1;Interleukin-1 beta;Interleukin-6;Interleukin-8;C-reactive protein; | — |
Countries
China
Contacts
Public ContactWei Yang
Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed