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Effect of Esketamine on Postoperative Delirium Induced by General Anesthesia during Elective Lobectomy in Adults

Effect of Esketamine on Postoperative Delirium Induced by General Anesthesia during Elective Lobectomy in Adults: A Multicentre, Double-blind, Randomised Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048116
Enrollment
Unknown
Registered
2021-07-02
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

Group A:None
Group B:None
Group C:None
Group D:None

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.ASA I-III grade; 2.Aged > 60 years old; 3.Gender is not limited; 4.General anesthesia and intubation patients with a body weight between 50-200 kg who are planning to undergo elective lobectomy.

Exclusion criteria

Exclusion criteria: 1.Emergency surgery; severe liver and kidney insufficiency; 2.Hypovolemia, shock or coma; 3.Suffering from mental system disease or central nervous system disorder; 4.Long-term use of psychotropic drugs; cognitive impairment; 5.Patients with severe arrhythmia or bradycardia; 6.Ketamine allergic patients; 7.Have a history of drug dependence; 8.Have used other sedative drugs in the past week.

Design outcomes

Primary

MeasureTime frame
Incidence of delirium;—

Countries

China

Contacts

Public ContactSong Xuemin

Zhongnan Hospital of Wuhan University

xueminsong@whu.edu.cn+86 18986073715

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026