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Clinical study of improved cardiopulmonary rehabilitation on lung function and Th17/Treg balance in patients with severe aspiration pneumonia

Clinical study of improved cardiopulmonary rehabilitation on lung function and Th17/Treg balance in patients with severe aspiration pneumonia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048115
Enrollment
Unknown
Registered
2021-07-02
Start date
2021-07-15
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inhalation pneumonia

Interventions

Experimental group:Modified cardiopulmonary rehabilitation
Control group:None

Sponsors

Ji'nan Eighth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.The diagnosis of aspiration pneumonia meets the diagnostic criteria of the consensus of experts on aspiration pneumonia in Japan in 2010: (1)Patients with risk factors of aspiration present fever, cough, expectoration, shortness of breath, tachycardia and other clinical manifestations; (2)Typical imaging findings: gravity-dependent pulmonary exudation; (3)There was definite aspiration. 2.Pneumonia severity index (PSI) score >= 91 was classified as IV-V severe pneumonia. 3.Patients above grade 3 in the drinking water test of depression field. 4.Over 60 years old. 5.Patients are able and willing to cooperate with cardiopulmonary rehabilitation.

Exclusion criteria

Exclusion criteria: 1.Complicated with chronic obstructive pulmonary disease, bronchial asthma, lung cancer, tuberculosis and other respiratory diseases; 2.Complicated with other serious diseases of the system; 3.People with cognitive or consciousness disorders or mental diseases; 4.Life expectancy less than half a year; 5.Poor treatment compliance; 6.Midway off can not follow visitors.

Design outcomes

Primary

MeasureTime frame
Pulmonary function;T lymphocyte subsets were measured;Interleukin-17;Interleukin-10;Computed tomography of the chest;Measurement of nutritional indexes;Transforming growth factor-ß;Swallowing function assessment;Life quality index;Mood state scale;

Countries

China

Contacts

Public ContactCai Renping

Ji'nan Eighth People's Hospital

cairenping@163.com+86 15006820725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026