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Clinical application of dacronin combined with lidocaine intravenous injection

Clinical application of dacronin combined with lidocaine intravenous injection

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048090
Enrollment
Unknown
Registered
2021-06-30
Start date
2021-06-28
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubation of anesthesia

Interventions

Dyclonine hydrochloride mucilage group:Dyclonine hydrochloride 3ml was applied to the front 1/3 of the endotracheal tube, and the remaining 7ml was administered orally and pharynx containing for 2 min
Lidocaine group:Lidocaine 1.5mg/kg intravenously
dyclonine hydrochloride mucilage combined with lidocaine group:Dyclonine hydrochloride 3ml was applied to the front 1/3 of the endotracheal tube, and the remaining 7ml was administered orally and phar

Sponsors

Chongqing University Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients requiring general anesthesia intubation; 2. ASA grade I and II; 3. Aged 18 to 65 years old; 4. Underwent short operations such as thyroid mass excision, breast mass excision, nasal endoscopic surgery, and oral intubation surgery in the department of stomatology; 5. The operation time was about 1 hour.

Exclusion criteria

Exclusion criteria: 1. Hypertension; 2. Arrhythmia; 3. Preoperative assessment of airway diseases such as difficult airway, asthma, chronic obstructive pulmonary disease.

Design outcomes

Primary

MeasureTime frame
Blood Pressure;Heart Rate;Agitation score;VAS score was used for throat pain;

Countries

China

Contacts

Public ContactLiu Hongliang

Chongqing University Cancer Hospital

liuhl75@163.com+86 13883686721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026