Stomach cancer
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. aged 18 to 75 years old; 2. ECOG score 0-1 points; 3. Pathological and/or cytologically confirmed diagnosis of gastric cancer; 4. The expected survival period >=3 months; 5. The main organs function normally, that is, they meet the following standards: (1) The standard of routine blood examination should meet: (no blood transfusion within 14 days) WBC =4.0×10^9/L; ANC =1.5×10^9/L; PLT =100×10^9/L; Hb =90g/L; (2) The biochemical inspection shall meet the following standards: BIL 50ml/min (Cockcroft-Gault formula); 6. Before joining the group, the heart function was good, no myocardial infarction occurred within half a year, and hypertension and other coronary heart diseases are currently within the controllable range; 7. No other uncontrollable benign diseases, such as lung, kidney, liver infection, etc., were not accompanied before enrollment; 8. Willing to sign an informed consent form, good medical compliance.
Exclusion criteria
Exclusion criteria: 1. Suffered from other malignant tumors in the past or at the same time, except for cured skin basal cell carcinoma and cervical carcinoma in situ; 2. Those who have been confirmed to be allergic to carrelizumab, apatinib, ticgio, oxaliplatin and/or its excipients; 3. Researchers believe that patients with a clear gastrointestinal bleeding tendency or/and abnormal coagulation function (INR>1.5) have a bleeding tendency; 4. Those who have undergone other anti-cancer treatments two months before enrollment or cannot be guaranteed to follow the research requirements after enrollment; 5. Pregnant or lactating women; 6. The investigator thinks it is not suitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival (PFS);Over all survival (OS);Adverse event; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective Response Rate (ORR);Surgical conversion rate; | — |
Countries
China
Contacts
The Affiliated Hospital of Youjiang Medical College