Helicobacter pylori
Conditions
Interventions
Experiental group:WeChat app-base reeducation+bismuth-containing quadruple therapies: BQT
The control group:Bismuth-containing quadruple therapies: BQT
Sponsors
The First Affiliated Hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years; 2. Patients with H. pylori infection confirmed by at least two positive tests from the rapid urease test, histology, culture, or stool antigen test, as well as individuals with a single positive 13C-urea breath test(need exclude those with DOB values close to the cut-off value(4-8))for health check 3. Previously untreated H. pylori infection; 4. Willingness to voluntarily participate in the study and sign informed consent; 5. Having a mobile device which can accept WeChat contents and having an ability to read them.
Exclusion criteria
Exclusion criteria: 1. Patients who had history of gastric surgery; 2. Patients with severe diseases such as liver disease, cardiac disease, kidney disease, malignant tumor and psychiatric disease; 3. Patients who had history of allergies to any of the study drugs; 4. Patients who had history of taking proton-pump inhibitor, H2 blocker drug, bismuth salt or antibiotics within four weeks before inclusion; 5. Patients with alcohol or drug abuse; 6. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H. pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance;Adverse events; | — |
Countries
China
Contacts
Public ContactZhang Jinyan
The First Affiliated Hospital of Xiamen University
Outcome results
None listed