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Effect of different volume co-loading on the dose requirements of prophylactic phenylephrine for preventing hypotension following spinal anesthesia for cesarean delivery

Effect of different volume co-loading on the dose requirements of prophylactic phenylephrine for preventing hypotension following spinal anesthesia for cesarean delivery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048002
Enrollment
Unknown
Registered
2021-06-28
Start date
2021-07-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal-induced hypotension

Interventions

Group A:Ringer's solution, infusion at 10ml/kg/h using an infusion pump
Group B:Ringer's solution, infusion at 20ml/kg/h using an infusion pump

Sponsors

Department of Anesthesia, Jiaxing University Affiliated Women and Children Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Full-term parturients who are scheduled to undergo elective cesarean section under combined spinal-epidural anesthesia; 2. ASA II.

Exclusion criteria

Exclusion criteria: 1. With regional anesthesia contraindications; 2. Body mass index (BMI) greater than 35 kg/m2; 3. Combined with hypertension, diabetes and other medical diseases; 4. With definite fetal distress.

Design outcomes

Primary

MeasureTime frame
effective/ineffective infusion rate of prophylactic phenylephrine. ;

Secondary

MeasureTime frame
Heart Rate;umbilical arterial blood pH ;lactated Ringer's solution during study period;total infusion of phenylephrine during study period;shivering;nausea and vomiting;Apgar scores at 1 minute after delivery;Apgar scores at 5 minutes after delivery;lactic acid;

Countries

China

Contacts

Public ContactFei Xiao

Jiaxing University Affiliated Women and Children Hospital

13706597501@163.com+86 137 0659 7501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026