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Observational study on the changes of intestinal flora in patients with thyroid carcinoma before and after 131 iodine treatment

Observational study on the changes of intestinal flora in patients with thyroid carcinoma before and after 131 iodine treatment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048000
Enrollment
Unknown
Registered
2021-06-28
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid cancer

Interventions

case group:Nil

Sponsors

Southwest Hospital, Third Military Medical University (Army Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pathologically diagnosed differentiated thyroid carcinoma (thyroid papillary carcinoma or follicular carcinoma); 2. Total thyroidectomy; 3. 131I treatment for the first time; 4. Patients are willing to participate in this study and sign the informed consent; 5. Patients voluntarily accept and abide by this experimental scheme, and receive reexamination and follow-up on time.

Exclusion criteria

Exclusion criteria: 1. History of other tumors; 2. Digestive system diseases or long-term gastrointestinal symptoms (such as digestive tract ulcers, inflammatory bowel disease, liver cirrhosis, chronic diarrhea, long-term constipation, etc.); 3. History of gastrointestinal surgery; 4. Long-term use of antibiotics, PPIs, or nonsteroidal anti-inflammatory drugs; 5. Taking other experimental drugs or participating in other clinical trials 3 months before being enrolled in the study; 6. Patients who should not be included in the study or could not cooperate with the study due to pregnancy, physical and mental illness or other reasons.

Design outcomes

Primary

MeasureTime frame
Flora composition;

Countries

China

Contacts

Public ContactHuang Dingde

Southwest Hospital, Third Military Medical University (Army Medical University)

huangdingde@126.com+86 13110133297

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026