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Explore the mechanism of repetitive transcranial magnetic stimulation intervention in tinnitus based on multi-modal functional magnetic resonance imaging

Explore the mechanism of repetitive transcranial magnetic stimulation intervention in tinnitus based on multi-modal functional magnetic resonance imaging

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047989
Enrollment
Unknown
Registered
2021-06-28
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus

Interventions

chronic tinnitus group:repetitive transcranial magnetic stimulation
acute and subacute tinnitus group:Nil
control group:Nil

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years and <70 years; 2. Tinnitus as the first complaint; 3. Able to complete all scale assessments independently; 4. All previous medications were ineffective; 5. Volunteered to participate in the study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Contraindications to rTMS: including metal foreign bodies in the skull, pacemakers, wires or metal stents in the heart, traumatic brain injury, increased intracranial pressure, abnormal brain signs or intracranial tumors, cerebrovascular disease, neurodegeneration of the brain, metal objects in or around the body that cannot be removed, history of epilepsy and family history of epilepsy, history of electroconvulsive therapy, pregnant women; 2. Objective tinnitus ; 3. Mental disorders such as hysterical tinnitus and hallucinations; 4. Those who had received transcranial magnetic stimulation; 5. A recent history of dizziness attacks or concomitant diseases such as Meniere's disease, suppurative otitis media, or sudden deafness; 6. Patients with communication problems and inability to cooperate. All patients signed an informed consent form prior to treatment. 7. Contraindications to MRI: (e.g., presence of ferromagnetic aneurysm clips, pacemakers); 8. Use of sedative or GABA-acting drugs in the last month 9. Other ear diseases that can cause tinnitus: Ménière's disease, otitis media, etc.

Design outcomes

Primary

MeasureTime frame
TFI score;

Countries

China

Contacts

Public ContactLiu Jisheng / Li Yonggang

The First Affiliated Hospital of Soochow University

liyonggang224@163.com+86 13506216162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026