gastroesophageal reflux disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with reflux related symptoms from the Second Affiliated Hospital of Chongqing Medical University; 2. Aged from 18 to 70 years, gender is not limited; 3. Volunteer to participate in this study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Cardiopulmonary insufficiency, cerebral apoplexy, obvious thoracic and abdominal aneurysm or in shock and coma and other patients who cannot tolerate examination; 2. Patients with suspected gastrointestinal bleeding, perforation, peritonitis, ascites and severe abdominal distension; 3. Cervical trauma, spinal deformity; 4. Patients with hemorrhagic diseases (including abnormal coagulation function); 5. Addiction and dependence of opioids or hypnotic drugs and long-term alcoholics; 6. Uncooperative, unable to communicate and suffering from neuropsychiatric diseases; 7. Corrosive inflammation of the upper digestive tract; 8. Pregnant or lactating woman; 9. People who are extremely uncooperative (mental abnormality, severe mental retardation); 10. People anesthetic drug allergy history or allergy constitution person; 11. Other researchers discussed the situation that they could not participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| saliva pspsin concentration; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Chongqing Medical University