Adenomyosis
Conditions
Interventions
experimental group1:HIFU + dienogest.
experimental group2:HIFU+GnRHa+Mirena
Sponsors
Shenzhen Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
30 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. A woman aged from 30 to 55 years with a diagnosis of adenomyosis; 2. All patients have progressively worsening dysmenorrhea (VAS>=3); 3. Ultrasound and MRI diagnosed as adenomyosis, the thickness of single-layer muscle wall is >=3 cm; 4. The sound channel organization hierarchy is clear and safe; 5. Persons with clear consciousness, barrier-free communication, and willing to cooperate with treatment; 6. No other surgical treatment for half a year before and after superablation treatment; 7. Exclude other gynecological diseases; 8. No HIFU treatment contraindications and willingly accept HIFU treatment; 9. Patients and their families informed consent; 10. No birth requirements.
Exclusion criteria
Exclusion criteria: 1. People with coagulation dysfunction; 2. Pregnant or lactating women; 3. Patients with heart, liver, kidney and other serious medical diseases; 4. Menstrual period or heavy vaginal bleeding; 5. Unable to maintain prone position and keep the bladder full; 6. Acute pelvic inflammation; 7. Suspected malignant lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The patient's postoperative pain relief (Visual analogue scoring VAS scoring method);Quality of life (SF-36) score;Extent of lesion reduction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Menstrual flow improvement (menstrual loss assessment chart PBAC); | — |
Countries
China
Contacts
Public ContactJin Ping
Shenzhen Maternal and Child Health Hospital
Outcome results
None listed